3ts7

X-ray diffraction
1.94Å resolution

CRYSTAL STRUCTURE OF FARNESYL DIPHOSPHATE SYNTHASE (TARGET EFI-501951) FROM Methylococcus capsulatus

Released:

Function and Biology Details

Reaction catalysed:
Geranyl diphosphate + isopentenyl diphosphate = diphosphate + (2E,6E)-farnesyl diphosphate
Biochemical function:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Geranyl transferase Chains: A, B
Molecule details ›
Chains: A, B
Length: 324 amino acids
Theoretical weight: 35.73 KDa
Source organism: Methylococcus capsulatus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q60AN0 (Residues: 1-300; Coverage: 100%)
Gene names: MCA0818, ispA
Sequence domains: Polyprenyl synthetase
Structure domains: Farnesyl Diphosphate Synthase

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P42212
Unit cell:
a: 114.592Å b: 114.592Å c: 113.19Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.221 0.219 0.266
Expression system: Escherichia coli BL21(DE3)