Function and Biology

Mouse Lin28A in complex with let-7d microRNA pre-element

Source organisms:
Biochemical function: zinc ion binding
Biological process: not assigned
Cellular component: not assigned

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF00098
Domain description: Zinc knuckle
Occurring in:
  1. Protein lin-28 homolog A
The deposited structure of PDB entry 3trz contains 6 copies of Pfam domain PF00098 (Zinc knuckle) in Protein lin-28 homolog A. Showing 1 copy in chain A.

PF00313
Domain description: 'Cold-shock' DNA-binding domain
Occurring in:
  1. Protein lin-28 homolog A
The deposited structure of PDB entry 3trz contains 6 copies of Pfam domain PF00313 ('Cold-shock' DNA-binding domain) in Protein lin-28 homolog A. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR002059
Domain description: Cold-shock protein, DNA-binding
Occurring in:
  1. Protein lin-28 homolog A
IPR001878
Domain description: Zinc finger, CCHC-type
Occurring in:
  1. Protein lin-28 homolog A
IPR012340
Domain description: Nucleic acid-binding, OB-fold
Occurring in:
  1. Protein lin-28 homolog A
IPR036875
Domain description: Zinc finger, CCHC-type superfamily
Occurring in:
  1. Protein lin-28 homolog A
IPR011129
Domain description: Cold shock domain
Occurring in:
  1. Protein lin-28 homolog A

Structure domains

CATH CATH domains
4.10.60.10
Class: Few Secondary Structures
Architecture: Irregular
Topology: HIV-1 Nucleocapsid Protein
Homology: Zinc finger, CCHC-type
Occurring in:
  1. Protein lin-28 homolog A
The deposited structure of PDB entry 3trz contains 6 copies of CATH domain 4.10.60.10 (HIV-1 Nucleocapsid Protein) in Protein lin-28 homolog A. Showing 1 copy in chain A.
2.40.50.140
Class: Mainly Beta
Architecture: Beta Barrel
Topology: OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Homology: Nucleic acid-binding proteins
Occurring in:
  1. Protein lin-28 homolog A
The deposited structure of PDB entry 3trz contains 6 copies of CATH domain 2.40.50.140 (OB fold (Dihydrolipoamide Acetyltransferase, E2P)) in Protein lin-28 homolog A. Showing 1 copy in chain A.