› 3tr3

X-ray diffraction
2.46Å resolution

Structure of a bolA protein homologue from Coxiella burnetii

Released:
DOI: 10.2210/pdb3tr3/pdb
PDB 3tr3 coloured by chain and viewed from the front.
PDB 3tr3 coloured by chain and viewed from the side.
PDB 3tr3 coloured by chain and viewed from the top.
Source organism: Coxiella burnetii
Primary publication:
Structural Genomics for Drug Design against the Pathogen Coxiella burnetii.
Franklin MC, Cheung J, Rudolph MJ, Burshteyn F, Cassidy M, Gary E, Hillerich B, Yao ZK, Carlier PR, Totrov M, Love JD
Proteins (2015)
PMID: 26033498

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
BolA family transcriptional regulator Chains: A, B
Molecule details ›
Chains: A, B
Length: 82 amino acids
Theoretical weight: 9.26 KDa
Source organism: Coxiella burnetii
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q83DW0 (Residues: 1-79; Coverage: 100%)
Gene names: CBU_0582, bolA
Sequence domains: BolA-like protein
Structure domains: BolA-like

Ligands and Environments

1 bound ligand:
Ligand CO 2 x CO
1 modified residue:
Ligand MSE 4 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4C, RIGAKU MICROMAX-007 HF
Spacegroup: P3121
Unit cell:
a: 66.245Å b: 66.245Å c: 118.009Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.188 0.186 0.22
Expression system: Escherichia coli BL21(DE3)

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Citations

4 review citations

Increasing cancer permeability by photodynamic priming: from microenvironment to mechanotransduction signaling.
Carigga Gutierrez et al. (2022)
3 more

1 mention without citation

Structural and spectroscopic insights into BolA-glutaredoxin complexes.
Roret et al. (2014)