X-ray diffraction
2.07Å resolution

Structure of the SPRY domain of human Ash2L

Source organism: Homo sapiens

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Set1/Ash2 histone methyltransferase complex subunit ASH2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 213 amino acids
Theoretical weight: 23.94 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q9UBL3 (Residues: 370-496, 516-617; Coverage: 33%)
Gene names: ASH2L, ASH2L1
Sequence domains: SPRY domain
Structure domains: Jelly Rolls

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-F
Spacegroup: P3121
Unit cell:
a: 115.289Å b: 115.289Å c: 105.78Å
α: 90° β: 90° γ: 120°
R R work R free
0.179 0.176 0.206
Expression system: Escherichia coli