› 3teq

X-ray diffraction
1.9Å resolution

Crystal structure of SOAR domain

Released:
DOI: 10.2210/pdb3teq/pdb
PDB entry 3teq coloured by chain, front view.
PDB entry 3teq coloured by chain, side view.
PDB entry 3teq coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural and mechanistic insights into the activation of Stromal interaction molecule 1 (STIM1).
Yang X, Jin H, Cai X, Li S, Shen Y
Proc Natl Acad Sci U S A 109 5657-62 (2012)
PMID: 22451904

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171770 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Stromal interaction molecule 1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 101 amino acids
Theoretical weight: 11.71 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q13586 (Residues: 344-444; Coverage: 15%)
Gene names: GOK, STIM1
Sequence domains: STIM1 Orai1-activating region
Structure domains: Helix Hairpins

Ligands and Environments

1 bound ligand:
Ligand PO4 5 x PO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P41212
Unit cell:
a: 90.584Å b: 90.584Å c: 104.919Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.221 0.219 0.249
Expression system: Escherichia coli

Quick links

Citations

44 review citations

Here, there, and everywhere: The importance of ER membrane contact sites.
Wu et al. (2018)
43 more

28 mentions without citation

Store-Operated Calcium Channels.
Prakriya et al. (2015)
27 more