3tde

X-ray diffraction
1.85Å resolution

Function and Biology Details

Reaction catalysed:
ATP + L-methionine + H(2)O = phosphate + diphosphate + S-adenosyl-L-methionine
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
S-adenosylmethionine synthase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 408 amino acids
Theoretical weight: 43.49 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli
UniProt:
  • Canonical: P9WGV1 (Residues: 2-403; Coverage: 100%)
Gene names: MTCY21B4.09, Rv1392, metK
Sequence domains:
Structure domains: GMP Synthetase; Chain A, domain 3

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-D
Spacegroup: P212121
Unit cell:
a: 76.88Å b: 85.1Å c: 245.42Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.165 0.164 0.194
Expression system: Escherichia coli