› 3swf

X-ray diffraction
2.14Å resolution

CNGA1 621-690 containing CLZ domain

Released:
DOI: 10.2210/pdb3swf/pdb
PDB entry 3swf coloured by chain, front view.
PDB entry 3swf coloured by chain, side view.
PDB entry 3swf coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
Molecular mechanism for 3:1 subunit stoichiometry of rod cyclic nucleotide-gated ion channels.
Shuart NG, Haitin Y, Camp SS, Black KD, Zagotta WN
Nat Commun 2 457 (2011)
PMID: 21878911

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-169400 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cyclic nucleotide-gated channel alpha-1 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 74 amino acids
Theoretical weight: 8.31 KDa
Source organism: Bos taurus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q00194 (Residues: 621-690; Coverage: 10%)
Gene names: CNCG, CNCG1, CNGA1
Sequence domains: C-terminal leucine zipper domain of cyclic nucleotide-gated channels
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand ZN 2 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.1
Spacegroup: P212121
Unit cell:
a: 32.01Å b: 76.71Å c: 113.11Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.204 0.203 0.23
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

16 review citations

Molecular mechanism of TRP channels.
Zheng J. (2013)
15 more

4 mentions without citation

Structural basis of properties, mechanisms, and channelopathy of cyclic nucleotide-gated channels.
Hu et al. (2023)
3 more