X-ray diffraction
2.2Å resolution

Clostridium difficile toxin A (TcdA) glucolsyltransferase domain


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Glucosyltransferase TcdA Chain: A
Molecule details ›
Chain: A
Length: 555 amino acids
Theoretical weight: 64.4 KDa
Source organism: Clostridioides difficile 630
Expression system: Priestia megaterium
  • Canonical: P16154 (Residues: 1-542; Coverage: 20%)
Gene names: tcdA, toxA
Sequence domains:
Structure domains: Methane Monooxygenase Hydroxylase; Chain G, domain 1

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P65
Unit cell:
a: 141.908Å b: 141.908Å c: 65.946Å
α: 90° β: 90° γ: 120°
R R work R free
0.184 0.182 0.227
Expression system: Priestia megaterium