3sri

X-ray diffraction
1.6Å resolution

Crystal structure of Plasmodium falciparum AMA1 in complex with a 29aa PfRON2 peptide

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-156202 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Apical membrane antigen 1 Chain: A
Molecule details ›
Chain: A
Length: 381 amino acids
Theoretical weight: 43.66 KDa
Source organism: Plasmodium falciparum CAMP/Malaysia
Expression system: Komagataella pastoris
UniProt:
  • Canonical: P50489 (Residues: 97-442; Coverage: 58%)
Gene names: AMA-1, PF83
Sequence domains: Apical membrane antigen 1
Structure domains: Hepatocyte Growth Factor
Rhoptry neck protein 2 Chain: B
Molecule details ›
Chain: B
Length: 29 amino acids
Theoretical weight: 3.04 KDa
Source organism: Plasmodium falciparum 3D7
Expression system: Not provided
UniProt:
  • Canonical: Q8IKV6 (Residues: 2027-2055; Coverage: 1%)
Gene name: PF3D7_1452000

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P21
Unit cell:
a: 70.724Å b: 38.137Å c: 72.078Å
α: 90° β: 97.72° γ: 90°
R-values:
R R work R free
0.177 0.176 0.195
Expression systems:
  • Komagataella pastoris
  • Not provided