3snp

X-ray diffraction
2.8Å resolution

Crystal structure analysis of iron regulatory protein 1 in complex with ferritin H IRE RNA

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct RNA molecule
Macromolecules (2 distinct):
Cytoplasmic aconitate hydratase Chains: A, B
Molecule details ›
Chains: A, B
Length: 908 amino acids
Theoretical weight: 100.78 KDa
Source organism: Oryctolagus cuniculus
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: Q01059 (Residues: 2-889; Coverage: 100%)
Gene names: ACO1, FRP, IREB1, IREBP
Sequence domains:
Structure domains:
ferritin H IRE RNA Chains: C, D
Molecule details ›
Chains: C, D
Length: 30 nucleotides
Theoretical weight: 9.57 KDa
Source organism: Xenopus laevis
Expression system: Not provided
Sequence domains: Iron response element I

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P21
Unit cell:
a: 109.555Å b: 80.851Å c: 142.873Å
α: 90° β: 92.03° γ: 90°
R-values:
R R work R free
0.199 0.198 0.218
Expression systems:
  • Saccharomyces cerevisiae
  • Not provided