X-ray diffraction
2Å resolution

Structure of Rheb-Y35A mutant in GDP- and GMPPNP-bound forms

Source organism: Homo sapiens
Entry authors: Mazhab-Jafari MT, Marshall CB, Ishiyama N, Vuk S, Ikura M

Function and Biology Details

Structure analysis Details

Assemblies composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
GTP-binding protein Rheb Chains: A, B
Molecule details ›
Chains: A, B
Length: 167 amino acids
Theoretical weight: 18.76 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q15382 (Residues: 3-169; Coverage: 91%)
Gene names: RHEB, RHEB2
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH3R
Unit cell:
a: 57.247Å b: 69.873Å c: 79.195Å
α: 90° β: 90° γ: 90°
R R work R free
0.166 0.162 0.214
Expression system: Escherichia coli