X-ray diffraction
2.25Å resolution

Structural Basis of Cytosolic DNA Recognition by Innate Immune Receptors


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Gamma-interferon-inducible protein 16 Chain: A
Molecule details ›
Chain: A
Length: 200 amino acids
Theoretical weight: 22.41 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: Q16666 (Residues: 571-766; Coverage: 25%)
Gene names: IFI16, IFNGIP1
Sequence domains: HIN-200/IF120x domain
Structure domains: Nucleic acid-binding proteins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-B
Spacegroup: R32
Unit cell:
a: 128.673Å b: 128.673Å c: 67.772Å
α: 90° β: 90° γ: 120°
R R work R free
0.18 0.177 0.229
Expression system: Escherichia coli BL21(DE3)