Function and Biology

Bacterial oligosaccharyltransferase PglB

Source organism: Campylobacter lari
Biochemical function: metal ion binding
Biological process: protein N-linked glycosylation via asparagine
Cellular component: plasma membrane

EC 2.4.99.19: Undecaprenyl-diphosphooligosaccharide--protein glycotransferase

Reaction catalysed:
Tritrans,heptacis-undecaprenyl diphosphooligosaccharide + [protein]-L-asparagine = tritrans,heptacis-undecaprenyl diphosphate + a glycoprotein with the oligosaccharide chain attached by N-beta-D-glycosyl linkage to protein L-asparagine
Systematic name:
Tritrans,heptacis-undecaprenyl-diphosphooligosaccharide:protein-L-asparagine N-beta-D-oligosaccharidotransferase
Alternative Name(s):
  • PglB

Sequence families

Pfam Protein families (Pfam)
PF02516
Domain description: Oligosaccharyl transferase STT3 subunit
Occurring in:
  1. Undecaprenyl-diphosphooligosaccharide--protein glycotransferase
1 copy of Pfam domain PF02516 (Oligosaccharyl transferase STT3 subunit) in Undecaprenyl-diphosphooligosaccharide--protein glycotransferase in PDB 3rce.

PF18527
Domain description: STT3/PglB C-terminal beta-barrel domain
Occurring in:
  1. Undecaprenyl-diphosphooligosaccharide--protein glycotransferase
1 copy of Pfam domain PF18527 (STT3/PglB C-terminal beta-barrel domain) in Undecaprenyl-diphosphooligosaccharide--protein glycotransferase in PDB 3rce.

InterPro InterPro annotations
IPR041563
Domain description: STT3 subunit PglB, C-terminal beta-barrel domain
Occurring in:
  1. Undecaprenyl-diphosphooligosaccharide--protein glycotransferase
IPR003674
Domain description: Oligosaccharyl transferase, STT3 subunit
Occurring in:
  1. Undecaprenyl-diphosphooligosaccharide--protein glycotransferase