› 3rbs

X-ray diffraction
1.85Å resolution

Crystal structure of the myomesin domains 10 and 11

Released:
DOI: 10.2210/pdb3rbs/pdb
PDB entry 3rbs coloured by chain, front view.
PDB entry 3rbs coloured by chain, side view.
PDB entry 3rbs coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Superhelical architecture of the myosin filament-linking protein myomesin with unusual elastic properties.
Pinotsis N, Chatziefthimiou SD, Berkemeier F, Beuron F, Mavridis IM, Konarev PV, Svergun DI, Morris E, Rief M, Wilmanns M
PLoS Biol 10 e1001261 (2012)
PMID: 22347812

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156475 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Myomesin-1 Chain: A
Molecule details ›
Chain: A
Length: 207 amino acids
Theoretical weight: 24.23 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P52179 (Residues: 1247-1447; Coverage: 12%)
Gene name: MYOM1
Sequence domains: Immunoglobulin I-set domain
Structure domains: Immunoglobulins

Ligands and Environments

2 bound ligands:
Ligand BME 3 x BME
Ligand NO3 2 x NO3
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: P212121
Unit cell:
a: 38.187Å b: 74.693Å c: 89.414Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.19 0.189 0.239
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

6 review citations

Force as a single molecule probe of multidimensional protein energy landscapes.
Zoldák et al. (2013)
5 more

7 mentions without citation

The sarcomeric M-region: a molecular command center for diverse cellular processes.
Hu et al. (2015)
6 more