3qwz

X-ray diffraction
2Å resolution

Crystal structure of FAF1 UBX-p97N-domain complex

Released:
Source organism: Homo sapiens
Entry authors: Park JK, Jeon H, Lee JJ, Kim KH, Lee KJ, Kim EE

Function and Biology Details

Reaction catalysed:
ATP + H(2)O = ADP + phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
hetero dimer (preferred)
hetero tetramer
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Transitional endoplasmic reticulum ATPase Chain: A
Molecule details ›
Chain: A
Length: 211 amino acids
Theoretical weight: 23.72 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P55072 (Residues: 1-208; Coverage: 26%)
Gene name: VCP
Sequence domains:
Structure domains:
FAS-associated factor 1 Chain: B
Molecule details ›
Chain: B
Length: 84 amino acids
Theoretical weight: 9.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UNN5 (Residues: 571-650; Coverage: 12%)
Gene names: CGI-03, FAF1, UBXD12, UBXN3A
Structure domains: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

Ligands and Environments

No bound ligands

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 4A
Spacegroup: C2
Unit cell:
a: 67.49Å b: 59.938Å c: 75.541Å
α: 90° β: 114.83° γ: 90°
R-values:
R R work R free
0.225 0.225 0.249
Expression system: Escherichia coli