› 3qwm

X-ray diffraction
2.39Å resolution

Crystal Structure of GEP100, the plextrin homology domain of IQ motif and SEC7 domain-containing protein 1 isoform a

Released:
DOI: 10.2210/pdb3qwm/pdb
PDB entry 3qwm coloured by chain, front view.
PDB entry 3qwm coloured by chain, side view.
PDB entry 3qwm coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Filippakopoulos P, Picaud S, Felletar I, Feller S, Janning M, Sabe H, Krojer T, Chaikuad A, Allerston C, von Delft F, Bountra C, Arrowsmith CH, Weigelt J, Edwards A, Knapp S, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-179523 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
IQ motif and SEC7 domain-containing protein 1 Chain: A
Molecule details ›
Chain: A
Length: 140 amino acids
Theoretical weight: 16.43 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q6DN90 (Residues: 743-880; Coverage: 14%)
Gene names: ARFGEP100, BRAG2, IQSEC1, KIAA0763
Sequence domains: PH domain
Structure domains: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03, DIAMOND BEAMLINE I04
Spacegroup: P6522
Unit cell:
a: 56.73Å b: 56.73Å c: 234.08Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.244 0.242 0.272
Expression system: Escherichia coli

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