EC 1.6.2.4: NADPH--hemoprotein reductase
Reaction catalysed:
NADPH + n oxidized hemoprotein = NADP(+) + n reduced hemoprotein
Systematic name:
NADPH:hemoprotein oxidoreductase
Alternative Name(s):
- Aldehyde reductase (NADPH-dependent)
- CPR
- Cytochrome P-450 reductase
- Cytochrome P450 reductase
- Cytochrome c reductase (reduced nicotinamide adenine dinucleotide phosphate, NADPH, NADPH-dependent)
- Dihydroxynicotinamide adenine dinucleotide phosphate-cytochrome c reductase
- FAD-cytochrome c reductase
- Ferrihemoprotein P-450 reductase
- NADP--cytochrome c reductase
- NADP--cytochrome reductase
- NADPH--cytochrome P-450 oxidoreductase
- NADPH--cytochrome P450 oxidoreductase
- NADPH--cytochrome P450 reductase
- NADPH--cytochrome c oxidoreductase
- NADPH--cytochrome c reductase
- NADPH--cytochrome p-450 reductase
- NADPH--ferricytochrome c oxidoreductase
- NADPH--ferrihemoprotein reductase
- NADPH-dependent cytochrome c reductase
- NADPH:P-450 reductase
- NADPH:P450 reductase
- NADPH:ferrihemoprotein oxidoreductase
- POR
- Reduced nicotinamide adenine dinucleotide phosphate-cytochrome c reductase
- Reductase, cytochrome c (reduced nicotinamide adenine dinucleotide phosphate)
- TPNH(2) cytochrome c reductase
- TPNH-cytochrome c reductase
GO terms
Biochemical function:
Biological process:
Cellular component:
Sequence families
Protein families (Pfam)
InterPro annotations
IPR039261
Domain description:
Ferredoxin-NADP reductase (FNR), nucleotide-binding domain
Occurring in:
Occurring in:
IPR023173
Domain description:
NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily
Occurring in:
Occurring in:
IPR003097
Domain description:
Sulfite reductase [NADPH] flavoprotein alpha-component-like, FAD-binding
Occurring in:
Occurring in:
Structure domains
CATH domains
2.40.30.10
Class:
Mainly Beta
Architecture:
Beta Barrel
Topology:
Elongation Factor Tu (Ef-tu); domain 3
Homology:
Translation factors
Occurring in:
3.40.50.80
Class:
Alpha Beta
Architecture:
3-Layer(aba) Sandwich
Topology:
Rossmann fold
Homology:
Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module
Occurring in:
1.20.990.10
Class:
Mainly Alpha
Architecture:
Up-down Bundle
Topology:
NADPH-cytochrome p450 Reductase; Chain A, domain 3
Homology:
NADPH-cytochrome p450 Reductase; Chain A, domain 3
Occurring in: