› 3q8c

X-ray diffraction
2.85Å resolution

Crystal structure of Protective Antigen W346F (pH 5.5)

Released:
DOI: 10.2210/pdb3q8c/pdb
PDB entry 3q8c coloured by chain, front view.
PDB entry 3q8c coloured by chain, side view.
PDB entry 3q8c coloured by chain, top view.
Source organism: Bacillus anthracis
Primary publication:
pH effects on binding between the anthrax protective antigen and the host cellular receptor CMG2.
Rajapaksha M, Lovell S, Janowiak BE, Andra KK, Battaile KP, Bann JG
Protein Sci 21 1467-80 (2012)
PMID: 22855243

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146574 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:

Ligands and Environments

1 bound ligand:
Ligand CA 2 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P212121
Unit cell:
a: 72.674Å b: 94.053Å c: 117.236Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.212 0.209 0.271
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Roles of Anthrax Toxin Receptor 2 in Anthrax Toxin Membrane Insertion and Pore Formation.
Sun et al. (2016)
1 more

1 mention without citation

pH effects on binding between the anthrax protective antigen and the host cellular receptor CMG2.
Rajapaksha et al. (2012)