› 3q6k

X-ray diffraction
2.52Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178480 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
43.2 kDa salivary protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 381 amino acids
Theoretical weight: 43.31 KDa
Source organism: Lutzomyia longipalpis
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q5WPU9 (Residues: 19-399; Coverage: 100%)
Gene name: LJM11_Clu9
Sequence domains: Major royal jelly protein
Structure domains: TolB, C-terminal domain

Ligands and Environments

2 bound ligands:
Ligand CIT 2 x CIT
Ligand SRO 2 x SRO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P6222
Unit cell:
a: 120.012Å b: 120.012Å c: 244.747Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.22 0.218 0.268
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

12 review citations

What's behind a sand fly bite? The profound effect of sand fly saliva on host hemostasis, inflammation and immunity.
Abdeladhim et al. (2014)
11 more

6 mentions without citation

Structure and function of a "yellow" protein from saliva of the sand fly Lutzomyia longipalpis that confers protective immunity against Leishmania major infection.
Xu et al. (2011)
5 more