3q60

X-ray diffraction
1.72Å resolution

Crystal structure of virulent allele ROP5B pseudokinase domain bound to ATP

Released:

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein kinase domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 371 amino acids
Theoretical weight: 41.22 KDa
Source organism: Toxoplasma gondii
Expression system: Escherichia coli
UniProt:
  • Canonical: F2YGR7 (Residues: 174-541; Coverage: 70%)
Gene names: ROP5, ROP5B, TGRH88_057710
Sequence domains: Kinase-like
Structure domains:

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-1
Spacegroup: P21212
Unit cell:
a: 123.358Å b: 69.329Å c: 43.385Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.18 0.179 0.21
Expression system: Escherichia coli