Function and Biology

The neutron crystallographic structure of inorganic pyrophosphatase from Thermococcus thioreducens

Source organism: Thermococcus thioreducens
Biochemical function: metal ion binding
Biological process: phosphate-containing compound metabolic process
Cellular component: cytosol

EC 3.6.1.1: Inorganic diphosphatase

Reaction catalysed:
Diphosphate + H(2)O = 2 phosphate
Systematic name:
Diphosphate phosphohydrolase
Alternative Name(s):
  • Inorganic pyrophosphatase
  • Pyrophosphate phosphohydrolase

Sequence family

Pfam Protein family (Pfam)
PF00719
Domain description: Inorganic pyrophosphatase
Occurring in:
  1. Inorganic pyrophosphatase
The deposited structure of PDB entry 3q3l contains 6 copies of Pfam domain PF00719 (Inorganic pyrophosphatase) in Inorganic pyrophosphatase. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR008162
Domain description: Inorganic pyrophosphatase
Occurring in:
  1. Inorganic pyrophosphatase
IPR036649
Domain description: Inorganic pyrophosphatase superfamily
Occurring in:
  1. Inorganic pyrophosphatase

Structure domain

CATH CATH domain
3.90.80.10
Class: Alpha Beta
Architecture: Alpha-Beta Complex
Topology: Inorganic Pyrophosphatase
Homology: Inorganic pyrophosphatase
Occurring in:
  1. Inorganic pyrophosphatase
The deposited structure of PDB entry 3q3l contains 6 copies of CATH domain 3.90.80.10 (Inorganic Pyrophosphatase) in Inorganic pyrophosphatase. Showing 1 copy in chain A.