We've built a new version of this page with an interactive 3D viewer. Try it out in beta and help us improve:

› 3q2f

X-ray diffraction
2.06Å resolution

Crystal Structure of the bromodomain of human BAZ2B in complex with a triazolo ligand

Released:
DOI: 10.2210/pdb3q2f/pdb
PDB entry 3q2f coloured by chain, front view.
PDB entry 3q2f coloured by chain, side view.
PDB entry 3q2f coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Muniz JRC, Filippakopoulos P, Picaud S, Felletar I, Keates T, von Delft F, Arrowsmith CH, Edwards AM, Weigelt J, Bountra C, Knapp S, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193783 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Bromodomain adjacent to zinc finger domain protein 2B Chain: A
Molecule details ›
Chain: A
Length: 117 amino acids
Theoretical weight: 13.62 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UIF8 (Residues: 2054-2168; Coverage: 5%)
Gene names: BAZ2B, KIAA1476
Sequence domains: Bromodomain
Structure domains: Bromodomain-like

Ligands and Environments

2 bound ligands:
Ligand OAM 1 x OAM
Ligand EDO 3 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E SUPERBRIGHT
Spacegroup: C2221
Unit cell:
a: 82.31Å b: 96.35Å c: 57.25Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.196 0.194 0.242
Expression system: Escherichia coli

Quick links