Function and Biology

Crystal structure of the PUMILIO-homology domain from Human PUMILIO2 in complex with erk2 NRE

Source organism: Homo sapiens
Biochemical function: RNA binding
Biological process: not assigned
Cellular component: not assigned

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00806
Domain description: Pumilio-family RNA binding repeat
Occurring in:
  1. Pumilio homolog 2
The deposited structure of PDB entry 3q0s contains 8 copies of Pfam domain PF00806 (Pumilio-family RNA binding repeat) in Pumilio homolog 2. Showing 8 copies in chain A.

InterPro InterPro annotations
IPR001313
Domain description: Pumilio RNA-binding repeat
Occurring in:
  1. Pumilio homolog 2
IPR033712
Domain description: Pumilio, RNA binding domain
Occurring in:
  1. Pumilio homolog 2
IPR016024
Domain description: Armadillo-type fold
Occurring in:
  1. Pumilio homolog 2
IPR033133
Domain description: Pumilio homology domain
Occurring in:
  1. Pumilio homolog 2
IPR011989
Domain description: Armadillo-like helical
Occurring in:
  1. Pumilio homolog 2

Structure domain

CATH CATH domain
1.25.10.10
Class: Mainly Alpha
Architecture: Alpha Horseshoe
Topology: Leucine-rich Repeat Variant
Homology: Leucine-rich Repeat Variant
Occurring in:
  1. Pumilio homolog 2
The deposited structure of PDB entry 3q0s contains 1 copy of CATH domain 1.25.10.10 (Leucine-rich Repeat Variant) in Pumilio homolog 2. Showing 1 copy in chain A.