PDBe 3pth

X-ray diffraction
1.7Å resolution

The PABC1 MLLE domain bound to the variant PAM2 motif of LARP4B

Released:
Source organism: Homo sapiens
Entry authors: Grimm C, Pelz JP

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Polyadenylate-binding protein 1 Chain: A
Molecule details ›
Chain: A
Length: 82 amino acids
Theoretical weight: 8.93 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P11940 (Residues: 543-621; Coverage: 12%)
Gene names: PAB1, PABP1, PABPC1, PABPC2
Sequence domains: Poly-adenylate binding protein, unique domain
Structure domains: c-terminal domain of poly(a) binding protein
La-related protein 4B Chain: B
Molecule details ›
Chain: B
Length: 15 amino acids
Theoretical weight: 1.65 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q92615 (Residues: 55-69; Coverage: 2%)
Gene names: KIAA0217, LARP4B, LARP5

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P212121
Unit cell:
a: 29.15Å b: 57.194Å c: 59.514Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.174 0.172 0.218
Expression systems:
  • Escherichia coli BL21
  • Not provided