3ppx

X-ray diffraction
1.91Å resolution

Crystal structure of the N1602A mutant of an engineered VWF A2 domain (N1493C and C1670S)

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
von Willebrand factor Chain: A
Molecule details ›
Chain: A
Length: 196 amino acids
Theoretical weight: 22.02 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P04275 (Residues: 1488-1674; Coverage: 7%)
Gene names: F8VWF, VWF
Sequence domains: von Willebrand factor type A domain
Structure domains: von Willebrand factor, type A domain

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P65
Unit cell:
a: 72.086Å b: 72.086Å c: 76.344Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.208 0.206 0.237
Expression system: Escherichia coli