X-ray diffraction
2.54Å resolution

Crystal structure of human ferredoxin-1 (FDX1) in complex with iron-sulfur cluster

Source organism: Homo sapiens
Entry authors: Chaikuad A, Johansson C, Krojer T, Yue WW, Phillips C, Bray JE, Pike ACW, Muniz JRC, Vollmar M, Weigelt J, Arrowsmith CH, Edwards AM, Bountra C, Kavanagh K, Oppermann U, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Adrenodoxin, mitochondrial Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 132 amino acids
Theoretical weight: 14.57 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P10109 (Residues: 61-184; Coverage: 67%)
Gene names: ADX, FDX1
Sequence domains: 2Fe-2S iron-sulfur cluster binding domain
Structure domains: Ubiquitin-like (UB roll)

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P32
Unit cell:
a: 76.576Å b: 76.576Å c: 234.41Å
α: 90° β: 90° γ: 120°
R R work R free
0.205 0.204 0.241
Expression system: Escherichia coli