PDBe 3p1j

X-ray diffraction
2.58Å resolution

Crystal structure of human GTPase IMAP family member 2 in the nucleotide-free state

Released:
Source organism: Homo sapiens
Entry authors: Shen L, Tempel W, Tong Y, Guan X, Nedyalkova L, Wernimont AK, Mackenzie F, Arrowsmith CH, Edwards AM, Bountra C, Weigelt J, Bochkarev A, Andrews DW, Park H, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
GTPase IMAP family member 2 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 209 amino acids
Theoretical weight: 23.18 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9UG22 (Residues: 19-226; Coverage: 62%)
Gene names: GIMAP2, IMAP2
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: P65
Unit cell:
a: 132.472Å b: 132.472Å c: 84.161Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.206 0.205 0.23
Expression system: Escherichia coli BL21(DE3)