3os8

X-ray diffraction
2.03Å resolution

Estrogen Receptor

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Estrogen receptor Chains: A, B
Molecule details ›
Chains: A, B
Length: 258 amino acids
Theoretical weight: 29.54 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P03372 (Residues: 299-553; Coverage: 43%)
  • Best match: P03372-2 (Residues: 254-441)
Gene names: ESR, ESR1, NR3A1
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor
Estrogen receptor Chains: C, D
Molecule details ›
Chains: C, D
Length: 258 amino acids
Theoretical weight: 29.47 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P03372 (Residues: 299-553; Coverage: 43%)
  • Best match: P03372-2 (Residues: 254-441)
Gene names: ESR, ESR1, NR3A1
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor

Ligands and Environments

1 bound ligand:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-1
Spacegroup: P1
Unit cell:
a: 53.698Å b: 58.569Å c: 93.461Å
α: 80.4° β: 74.85° γ: 62.79°
R-values:
R R work R free
0.188 0.186 0.228
Expression system: Escherichia coli