3oed

X-ray diffraction
3.16Å resolution

The structure of the complex between complement receptor CR2 and its ligand complement fragment C3d

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Complement C3d fragment Chains: A, B
Molecule details ›
Chains: A, B
Length: 310 amino acids
Theoretical weight: 34.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P01024 (Residues: 996-1303; Coverage: 19%)
Gene names: C3, CPAMD1
Structure domains: Glycosyltransferase
Complement receptor type 2 Chains: C, D
Molecule details ›
Chains: C, D
Length: 135 amino acids
Theoretical weight: 14.83 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P20023 (Residues: 19-153; Coverage: 13%)
Gene names: C3DR, CR2
Sequence domains: Sushi repeat (SCR repeat)
Structure domains: Complement Module, domain 1

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: R32
Unit cell:
a: 146.12Å b: 146.12Å c: 253.06Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.189 0.189 0.259
Expression system: Escherichia coli BL21