3nz8

X-ray diffraction
2.7Å resolution

Crystal structure of the HIV-2 neutralizing Fab fragment 7C8

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Mouse anti V3 antibody 7C8 Fab, heavy chain Chains: A, H
Molecule details ›
Chains: A, H
Length: 221 amino acids
Theoretical weight: 23.75 KDa
Source organism: Mus musculus
Expression system: Mus musculus
Structure domains: Immunoglobulins
Mouse anti V3 antibody 7C8 Fab, light chain Chains: B, L
Molecule details ›
Chains: B, L
Length: 218 amino acids
Theoretical weight: 24.13 KDa
Source organism: Mus musculus
Expression system: Mus musculus
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MAX II BEAMLINE I711
Spacegroup: P3221
Unit cell:
a: 100.071Å b: 100.071Å c: 196.763Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.229 0.226 0.273
Expression system: Mus musculus