3nkr

X-ray diffraction
1.7Å resolution

Crystal structure of mouse autotaxin in complex with 22:6-LPA

Released:
Source organism: Mus musculus
Entry authors: Nishimasu H, Ishitani R, Mihara E, Takagi J, Aoki J, Nureki O

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (3 distinct):
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 Chain: A
Molecule details ›
Chain: A
Length: 831 amino acids
Theoretical weight: 95.76 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q9R1E6 (Residues: 36-862; Coverage: 99%)
Gene names: Enpp2, Npps2, Pdnp2
Sequence domains:
Structure domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE AR-NE3A
Spacegroup: P21
Unit cell:
a: 61.544Å b: 94.107Å c: 75.308Å
α: 90° β: 95.26° γ: 90°
R-values:
R R work R free
0.194 0.192 0.22
Expression system: Homo sapiens