› 3ndo

X-ray diffraction
1.25Å resolution

Function and Biology Details

Reaction catalysed: 
2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-106258 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Deoxyribose-phosphate aldolase Chains: A, B
Molecule details ›
Chains: A, B
Length: 231 amino acids
Theoretical weight: 22.75 KDa
Source organism: Mycolicibacterium smegmatis
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A0QQY7 (Residues: 1-227; Coverage: 100%)
Gene names: MSMEG_0922, deoC
Sequence domains: DeoC/LacD family aldolase
Structure domains: Aldolase class I

Ligands and Environments

3 bound ligands:
Ligand NH4 1 x NH4
Ligand UNL 2 x UNL
Ligand GOL 4 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: P21
Unit cell:
a: 46.98Å b: 73.2Å c: 64.38Å
α: 90° β: 91° γ: 90°
R-values:
R R work R free
0.124 0.123 0.144
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

6 review citations

Pleiotropic Functions of Tumor Suppressor WWOX in Normal and Cancer Cells.
Abu-Remaileh et al. (2015)
5 more

1 mention without citation

Functional Monomerization of a ClC-Type Fluoride Transporter.
Last et al. (2015)