› 3ncv

X-ray diffraction
2.4Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-177073 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA mismatch repair protein MutL Chains: A, B
Molecule details ›
Chains: A, B
Length: 220 amino acids
Theoretical weight: 23.98 KDa
Source organism: Neisseria gonorrhoeae FA 1090
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5F8M6 (Residues: 460-658; Coverage: 30%)
Gene names: NGO0744, mutL
Sequence domains: MutL C terminal dimerisation domain
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: P21
Unit cell:
a: 49.5Å b: 62.1Å c: 92.1Å
α: 90° β: 104.6° γ: 90°
R-values:
R R work R free
0.221 0.216 0.272
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Evolution of the methyl directed mismatch repair system in Escherichia coli.
Putnam CD. (2016)
3 more

7 mentions without citation

Dominant mutations in S. cerevisiae PMS1 identify the Mlh1-Pms1 endonuclease active site and an exonuclease 1-independent mismatch repair pathway.
Smith et al. (2013)
6 more