› 3nau

X-ray diffraction
2.7Å resolution

Crystal structure of ZHX2 HD2 (zinc-fingers and homeoboxes protein 2, homeodomain 2)

Released:
DOI: 10.2210/pdb3nau/pdb
PDB 3nau coloured by chain and viewed from the front.
PDB 3nau coloured by chain and viewed from the side.
PDB 3nau coloured by chain and viewed from the top.
Source organism: Homo sapiens
Primary publication:
Novel structural features in two ZHX homeodomains derived from a systematic study of single and multiple domains.
Bird LE, Ren J, Nettleship JE, Folkers GE, Owens RJ, Stammers DK
OpenAccess logo BMC Struct Biol 10 13 (2010)
PMID: 20509910

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Zinc fingers and homeoboxes protein 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 66 amino acids
Theoretical weight: 7.98 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9Y6X8 (Residues: 444-501; Coverage: 7%)
Gene names: AFR1, KIAA0854, RAF, ZHX2
Structure domains: Homeodomain-like

Ligands and Environments

1 bound ligand:
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: C2
Unit cell:
a: 96.71Å b: 60.67Å c: 27.71Å
α: 90° β: 95.34° γ: 90°
R-values:
R R work R free
0.207 0.203 0.267
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Host Transcription Factors in Hepatitis B Virus RNA Synthesis.
Turton et al. (2020)
2 more

1 mention without citation

Novel structural features in two ZHX homeodomains derived from a systematic study of single and multiple domains.
Bird et al. (2010)