3n1q

X-ray diffraction
2.89Å resolution

Crystal Structure of DhhN bound to CDOFn3

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Desert hedgehog protein N-product Chains: A, B, E
Molecule details ›
Chains: A, B, E
Length: 170 amino acids
Theoretical weight: 19.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O43323 (Residues: 24-189; Coverage: 44%)
Gene name: DHH
Structure domains: Muramoyl-pentapeptide Carboxypeptidase; domain 2
Cell adhesion molecule-related/down-regulated by oncogenes Chains: C, D, F
Molecule details ›
Chains: C, D, F
Length: 102 amino acids
Theoretical weight: 11.66 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q4KMG0 (Residues: 826-924; Coverage: 8%)
Gene names: CDO, CDON
Sequence domains: Fibronectin type III domain
Structure domains: Immunoglobulins

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E SUPERBRIGHT
Spacegroup: P21
Unit cell:
a: 45.715Å b: 100.265Å c: 97.26Å
α: 90° β: 98.98° γ: 90°
R-values:
R R work R free
0.24 0.237 0.288
Expression system: Escherichia coli