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Glycogen phosphorylase complexed with 4-trifluoromethylbenzaldehyde-4-(beta-D-glucopyranosyl)-thiosemicarbazone

X-ray diffraction
2.07Å resolution
PDB entry 3ms4 coloured by chain, front view.
PDB entry 3ms4 coloured by chain, side view.
PDB entry 3ms4 coloured by chain, top view.
Source organism: Oryctolagus cuniculus
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Glycogen phosphorylase, muscle form
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Multimeric state: homo dimer
Accessible surface area: 57073.16 Å2
Buried surface area: 4597.99 Å2
Dissociation area: 2,298.99 Å2
Dissociation energy (ΔGdiss): 12.95 kcal/mol
Dissociation entropy (TΔSdiss): 16.02 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-132556

Macromolecules

Glycogen phosphorylase, muscle form
Chain: A
Length: 842 amino acids
Theoretical weight: 97.52 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: P00489 (Residues: 2-843; Coverage: 100%)
Gene name: PYGM
Pfam: Carbohydrate phosphorylase
InterPro:
CATH: Glycogen Phosphorylase B;
Glycogen phosphorylase, muscle form in PDB entry 3ms4, assembly 1, front view.
Glycogen phosphorylase, muscle form in PDB entry 3ms4, assembly 1, side view.
Glycogen phosphorylase, muscle form in PDB entry 3ms4, assembly 1, top view.
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