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CASK-4M CaM Kinase Domain, AMPPNP

X-ray diffraction
2.1Å resolution
PDB entry 3mfs coloured by chain, front view.
PDB entry 3mfs coloured by chain, side view.
PDB entry 3mfs coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Peripheral plasma membrane protein CASK
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Multimeric state: monomeric
Accessible surface area: 14553.7 Å2
Buried surface area: 782.84 Å2
Dissociation area: 391.42 Å2
Dissociation energy (ΔGdiss): -1.26 kcal/mol
Dissociation entropy (TΔSdiss): 5.3 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-127208

Macromolecules

Peripheral plasma membrane protein CASK
Chain: A
Length: 351 amino acids
Theoretical weight: 39.29 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O14936 (Residues: 1-337; Coverage: 36%)
Gene names: CASK, LIN2
Pfam: Protein kinase domain
InterPro:
CATH:
Peripheral plasma membrane protein CASK in PDB entry 3mfs, assembly 1, front view.
Peripheral plasma membrane protein CASK in PDB entry 3mfs, assembly 1, side view.
Peripheral plasma membrane protein CASK in PDB entry 3mfs, assembly 1, top view.
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