PDBe 3mcb

X-ray diffraction
1.9Å resolution

Crystal structure of NAC domains of human nascent polypeptide-associated complex (NAC)

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Nascent polypeptide-associated complex subunit alpha Chain: A
Molecule details ›
Chain: A
Length: 54 amino acids
Theoretical weight: 6 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q13765 (Residues: 79-132; Coverage: 25%)
Gene names: HSD48, NACA
Structure domains: Ubiquitin Ligase Nedd4; Chain: W;
Transcription factor BTF3 Chain: B
Molecule details ›
Chain: B
Length: 58 amino acids
Theoretical weight: 6.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P20290 (Residues: 97-154; Coverage: 28%)
Gene names: BTF3, NACB, OK/SW-cl.8
Structure domains: Ubiquitin Ligase Nedd4; Chain: W;

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-17A
Spacegroup: P6522
Unit cell:
a: 59.794Å b: 59.794Å c: 156.763Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.194 0.188 0.247
Expression system: Escherichia coli