3mb3

X-ray diffraction
2.25Å resolution

Crystal Structure of the second bromodomain of Pleckstrin homology domain interacting protein (PHIP)

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
PH-interacting protein Chain: A
Molecule details ›
Chain: A
Length: 135 amino acids
Theoretical weight: 16.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8WWQ0 (Residues: 1302-1434; Coverage: 7%)
Gene names: DCAF14, PHIP, WDR11
Sequence domains: Bromodomain
Structure domains: Bromodomain-like

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P3121
Unit cell:
a: 92.09Å b: 92.09Å c: 76.12Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.208 0.206 0.257
Expression system: Escherichia coli BL21(DE3)