3m5p

X-ray diffraction
1.65Å resolution

Glucose-6-phosphate isomerase from Francisella tularensis complexed with fructose-6-phosphate.

Released:
Entry authors: Osipiuk J, Maltseva N, Hasseman J, Anderson WF, Joachimiak A, Center for Structural Genomics of Infectious Diseases (CSGID)

Function and Biology Details

Reaction catalysed:
Alpha-D-glucose 6-phosphate = beta-D-fructofuranose 6-phosphate
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glucose-6-phosphate isomerase Chain: A
Molecule details ›
Chain: A
Length: 543 amino acids
Theoretical weight: 61.94 KDa
Source organism: Francisella tularensis subsp. tularensis
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5NFC4 (Residues: 1-540; Coverage: 100%)
Gene names: FTT_1315c, pgi
Sequence domains: Phosphoglucose isomerase
Structure domains:

Ligands and Environments

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-BM
Spacegroup: P3221
Unit cell:
a: 114.272Å b: 114.272Å c: 83.723Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.132 0.131 0.16
Expression system: Escherichia coli