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Structure of a Longitudinal Actin Dimer Assembled by Tandem W Domains

Source organisms:
Biochemical function: actin monomer binding
Biological process: mesenchyme migration
Cellular component: skeletal muscle myofibril

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GO terms

Sequence families

Pfam Protein families (Pfam)
PF02205
Domain description: WH2 motif
Occurring in:
  1. Actin nucleation-promoting factor WASL; Thymosin beta-4
The deposited structure of PDB entry 3m3n contains 2 copies of Pfam domain PF02205 (WH2 motif) in Actin nucleation-promoting factor WASL. Showing 2 copies in chain C [auth W].

PF00022
Domain description: Actin
Occurring in:
  1. Actin, alpha skeletal muscle
The deposited structure of PDB entry 3m3n contains 2 copies of Pfam domain PF00022 (Actin) in Actin, alpha skeletal muscle. Showing 1 copy in chain A.

PF01290
Domain description: Thymosin beta-4 family
Occurring in:
  1. Actin nucleation-promoting factor WASL; Thymosin beta-4

InterPro InterPro annotations
IPR004000
Domain description: Actin family
Occurring in:
  1. Actin, alpha skeletal muscle
IPR003124
Domain description: WH2 domain
Occurring in:
  1. Actin nucleation-promoting factor WASL; Thymosin beta-4
IPR001152
Domain description: Beta-thymosin
Occurring in:
  1. Actin nucleation-promoting factor WASL; Thymosin beta-4
IPR004001
Domain description: Actin, conserved site
Occurring in:
  1. Actin, alpha skeletal muscle
IPR043129
Domain description: ATPase, nucleotide binding domain
Occurring in:
  1. Actin, alpha skeletal muscle
IPR011026
Domain description: Actin nucleation-promoting factor WAS, C-terminal
Occurring in:
  1. Actin nucleation-promoting factor WASL; Thymosin beta-4
IPR020902
Domain description: Actin/actin-like conserved site
Occurring in:
  1. Actin, alpha skeletal muscle
IPR038386
Domain description: Beta-thymosin superfamily
Occurring in:
  1. Actin nucleation-promoting factor WASL; Thymosin beta-4

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