3m3d

X-ray diffraction
2.34Å resolution

Crystal structure of Acetylcholinesterase in complex with Xenon

Released:
Source organism: Tetronarce californica
Entry authors: Behnen J, Brumshtein B, Toker L, Silman I, Sussman JL, Klebe G, Heine A

Function and Biology Details

Reaction catalysed:
Acetylcholine + H(2)O = choline + acetate
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Acetylcholinesterase Chain: A
Molecule details ›
Chain: A
Length: 543 amino acids
Theoretical weight: 61.33 KDa
Source organism: Tetronarce californica
UniProt:
  • Canonical: P04058 (Residues: 22-564; Coverage: 96%)
Gene name: ache
Sequence domains: Carboxylesterase family
Structure domains: Rossmann fold

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P3121
Unit cell:
a: 111.769Å b: 111.769Å c: 137.232Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.19 0.19 0.2