3lxx

X-ray diffraction
2.15Å resolution

Crystal structure of human GTPase IMAP family member 4

Released:
Source organism: Homo sapiens
Entry authors: Shen Y, Nedyalkova L, Tong Y, Tempel W, Mackenzie F, Arrowsmith CH, Edwards AM, Bountra C, Weigelt J, Bochkarev A, Andrews DW, Park H, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
GTPase IMAP family member 4 Chain: A
Molecule details ›
Chain: A
Length: 239 amino acids
Theoretical weight: 27.33 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9NUV9 (Residues: 20-240; Coverage: 67%)
Gene names: GIMAP4, IAN1, IMAP4, MSTP062
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

3 bound ligands:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-B
Spacegroup: C2221
Unit cell:
a: 41.266Å b: 102.663Å c: 100.555Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.254 0.252 0.291
Expression system: Escherichia coli