3lvx

X-ray diffraction
1.63Å resolution

Crystal structure of human alpha-defensin 1 (I6A mutant)

Released:
Source organism: Homo sapiens

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo 48-mer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neutrophil defensin 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 30 amino acids
Theoretical weight: 3.41 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P59665 (Residues: 65-94; Coverage: 40%)
Gene names: DEF1, DEFA1, DEFA1B, DEFA2, MRS
Sequence domains: Mammalian defensin

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: F432
Unit cell:
a: 118.069Å b: 118.069Å c: 118.069Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.169 0.168 0.174
Expression system: Not provided