EC 3.1.1.7: Acetylcholinesterase
Reaction catalysed:
Acetylcholine + H(2)O = choline + acetate
Systematic name:
Acetylcholine acetylhydrolase
Alternative Name(s):
- AcCholE
- Acetyl.beta-methylcholinesterase
- Acetylcholine hydrolase
- Acetylthiocholinesterase
- Choline esterase I
- Cholinesterase
- True cholinesterase
GO terms
Biochemical function:
- carboxylic ester hydrolase activity
- obsolete protein self-association
- laminin binding
- protein homodimerization activity
- identical protein binding
- acetylcholine binding
- serine hydrolase activity
- hydrolase activity
- collagen binding
- protein binding
- cholinesterase activity
- acetylcholinesterase activity
- amyloid-beta binding
Biological process:
- positive regulation of cold-induced thermogenesis
- acetylcholine receptor signaling pathway
- retina development in camera-type eye
- positive regulation of protein secretion
- amyloid precursor protein metabolic process
- negative regulation of synaptic transmission, cholinergic
- receptor internalization
- choline metabolic process
- synapse assembly
- nervous system development
- cell adhesion
- acetylcholine catabolic process
- osteoblast development
- regulation of receptor recycling
- acetylcholine catabolic process in synaptic cleft
Protein family (Pfam)
InterPro annotations
CATH domain