PDBe 3l7u

X-ray diffraction
2.1Å resolution

Crystal structure of human NM23-H1

Released:
Source organism: Homo sapiens
Primary publication:
Refined Structure of Human NM23-H1 from a Hexagonal Crystal
BULL.KOREAN CHEM.SOC. 31 1397-1399 (2010)

Function and Biology Details

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nucleoside diphosphate kinase A Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 172 amino acids
Theoretical weight: 19.34 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P15531 (Residues: 1-152; Coverage: 100%)
Gene names: NDPKA, NM23, NME1
Sequence domains: Nucleoside diphosphate kinase
Structure domains: Nucleoside diphosphate kinase-like domain

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-5A
Spacegroup: P6122
Unit cell:
a: 154.51Å b: 154.51Å c: 111.821Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.224 0.224 0.242
Expression system: Escherichia coli