PDBe 3l5i

X-ray diffraction
1.9Å resolution

Crystal structure of FnIII domains of human GP130 (Domains 4-6)

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Interleukin-6 receptor subunit beta Chain: A
Molecule details ›
Chain: A
Length: 290 amino acids
Theoretical weight: 33.09 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P40189 (Residues: 323-612; Coverage: 32%)
Gene name: IL6ST
Sequence domains: Fibronectin type III domain
Structure domains: Immunoglobulins

Ligands and Environments

2 bound ligands:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: P212121
Unit cell:
a: 41.565Å b: 75.347Å c: 107.185Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.181 0.181 0.222
Expression system: Escherichia coli