PDBe 3l5h

X-ray diffraction
3.6Å resolution

Crystal structure of the full ectodomain of human gp130: New insights into the molecular assembly of receptor complexes

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Interleukin-6 receptor subunit beta Chain: A
Molecule details ›
Chain: A
Length: 589 amino acids
Theoretical weight: 67.01 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P40189 (Residues: 24-612; Coverage: 66%)
Gene name: IL6ST
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: P21
Unit cell:
a: 89.001Å b: 51.821Å c: 167.157Å
α: 90° β: 102.17° γ: 90°
R-values:
R R work R free
0.267 0.263 0.335
Expression system: Spodoptera frugiperda