3l32 Citations

Structure of the dimerization domain of the rabies virus phosphoprotein.

J. Virol. 84 3707-10 (2010)
Cited: 42 times
EuropePMC logo PMID: 20089657

Abstract

The crystal structure of the dimerization domain of rabies virus phosphoprotein was determined. The monomer consists of two alpha-helices that make a helical hairpin held together mainly by hydrophobic interactions. The monomer has a hydrophilic and a hydrophobic face, and in the dimer two monomers pack together through their hydrophobic surfaces. This structure is very different from the dimerization domain of the vesicular stomatitis virus phosphoprotein and also from the tetramerization domain of the Sendai virus phosphoprotein, suggesting that oligomerization is conserved but not structure.

Reviews - 3l32 mentioned but not cited (1)

Articles - 3l32 mentioned but not cited (3)

  1. Structure of the dimerization domain of the rabies virus phosphoprotein. Ivanov I, Crépin T, Jamin M, Ruigrok RW. J. Virol. 84 3707-3710 (2010)
  2. Solution and crystallographic structures of the central region of the phosphoprotein from human metapneumovirus. Leyrat C, Renner M, Harlos K, Grimes JM. PLoS ONE 8 e80371 (2013)
  3. Crystal Structure of the Marburg Virus VP35 Oligomerization Domain. Bruhn JF, Kirchdoerfer RN, Urata SM, Li S, Tickle IJ, Bricogne G, Saphire EO. J. Virol. 91 (2017)


Reviews citing this publication (11)

  1. Structural insights into RNA polymerases of negative-sense RNA viruses. Te Velthuis AJW, Grimes JM, Fodor E. Nat Rev Microbiol (2021)
  2. Negri bodies and other virus membrane-less replication compartments. Nevers Q, Albertini AA, Lagaudrière-Gesbert C, Gaudin Y. Biochim Biophys Acta Mol Cell Res 1867 118831 (2020)
  3. Unraveling virus relationships by structure-based phylogenetic classification. Ng WM, Stelfox AJ, Bowden TA. Virus Evol 6 veaa003 (2020)
  4. Status of antiviral therapeutics against rabies virus and related emerging lyssaviruses. Du Pont V, Plemper RK, Schnell MJ. Curr Opin Virol 35 1-13 (2019)
  5. How order and disorder within paramyxoviral nucleoproteins and phosphoproteins orchestrate the molecular interplay of transcription and replication. Longhi S, Bloyet LM, Gianni S, Gerlier D. Cell. Mol. Life Sci. 74 3091-3118 (2017)
  6. Multivalent IDP assemblies: Unique properties of LC8-associated, IDP duplex scaffolds. Clark SA, Jespersen N, Woodward C, Barbar E. FEBS Lett. 589 2543-2551 (2015)
  7. The paramyxovirus polymerase complex as a target for next-generation anti-paramyxovirus therapeutics. Cox R, Plemper RK. Front Microbiol 6 459 (2015)
  8. RNA synthetic mechanisms employed by diverse families of RNA viruses. McDonald SM. Wiley Interdiscip Rev RNA 4 351-367 (2013)
  9. The polymerase of negative-stranded RNA viruses. Morin B, Kranzusch PJ, Rahmeh AA, Whelan SP. Curr Opin Virol 3 103-110 (2013)
  10. Mutual effects of disorder and order in fusion proteins between intrinsically disordered domains and fluorescent proteins. Lotti M, Longhi S. Mol Biosyst 8 105-113 (2012)
  11. Structural disorder within paramyxovirus nucleoproteins and phosphoproteins. Habchi J, Longhi S. Mol Biosyst 8 69-81 (2012)

Articles citing this publication (27)

  1. Characterization of the interactions between the nucleoprotein and the phosphoprotein of Henipavirus. Habchi J, Blangy S, Mamelli L, Jensen MR, Blackledge M, Darbon H, Oglesbee M, Shu Y, Longhi S. J. Biol. Chem. 286 13583-13602 (2011)
  2. Structure of the tetramerization domain of measles virus phosphoprotein. Communie G, Crépin T, Maurin D, Jensen MR, Blackledge M, Ruigrok RW. J. Virol. 87 7166-7169 (2013)
  3. Detecting remote sequence homology in disordered proteins: discovery of conserved motifs in the N-termini of Mononegavirales phosphoproteins. Karlin D, Belshaw R. PLoS ONE 7 e31719 (2012)
  4. Structural and functional characterization of the mumps virus phosphoprotein. Cox R, Green TJ, Purushotham S, Deivanayagam C, Bedwell GJ, Prevelige PE, Luo M. J. Virol. 87 7558-7568 (2013)
  5. Plasticity in structural and functional interactions between the phosphoprotein and nucleoprotein of measles virus. Shu Y, Habchi J, Costanzo S, Padilla A, Brunel J, Gerlier D, Oglesbee M, Longhi S. J. Biol. Chem. 287 11951-11967 (2012)
  6. A novel nuclear trafficking module regulates the nucleocytoplasmic localization of the rabies virus interferon antagonist, P protein. Oksayan S, Wiltzer L, Rowe CL, Blondel D, Jans DA, Moseley GW. J. Biol. Chem. 287 28112-28121 (2012)
  7. Crystal structure of the nipah virus phosphoprotein tetramerization domain. Bruhn JF, Barnett KC, Bibby J, Thomas JM, Keegan RM, Rigden DJ, Bornholdt ZA, Saphire EO. J. Virol. 88 758-762 (2014)
  8. Focal adhesion kinase is involved in rabies virus infection through its interaction with viral phosphoprotein P. Fouquet B, Nikolic J, Larrous F, Bourhy H, Wirblich C, Lagaudrière-Gesbert C, Blondel D. J. Virol. 89 1640-1651 (2015)
  9. Negri bodies are viral factories with properties of liquid organelles. Nikolic J, Le Bars R, Lama Z, Scrima N, Lagaudrière-Gesbert C, Gaudin Y, Blondel D. Nat Commun 8 58 (2017)
  10. Biochemical and structural studies of the oligomerization domain of the Nipah virus phosphoprotein: evidence for an elongated coiled-coil homotrimer. Blocquel D, Beltrandi M, Erales J, Barbier P, Longhi S. Virology 446 162-172 (2013)
  11. Cytorhabdovirus P protein suppresses RISC-mediated cleavage and RNA silencing amplification in planta. Mann KS, Johnson KN, Carroll BJ, Dietzgen RG. Virology 490 27-40 (2016)
  12. Asymmetric packaging of polymerases within vesicular stomatitis virus. Hodges J, Tang X, Landesman MB, Ruedas JB, Ghimire A, Gudheti MV, Perrault J, Jorgensen EM, Gerton JM, Saffarian S. Biochem. Biophys. Res. Commun. 440 271-276 (2013)
  13. An In Vitro RNA Synthesis Assay for Rabies Virus Defines Ribonucleoprotein Interactions Critical for Polymerase Activity. Morin B, Liang B, Gardner E, Ross RA, Whelan SPJ. J. Virol. 91 (2017)
  14. Coiled-coil deformations in crystal structures: the measles virus phosphoprotein multimerization domain as an illustrative example. Blocquel D, Habchi J, Durand E, Sevajol M, Ferron F, Erales J, Papageorgiou N, Longhi S. Acta Crystallogr. D Biol. Crystallogr. 70 1589-1603 (2014)
  15. Structure of a rabies virus polymerase complex from electron cryo-microscopy. Horwitz JA, Jenni S, Harrison SC, Whelan SPJ. Proc Natl Acad Sci U S A 117 2099-2107 (2020)
  16. Growth signalobody selects functional intrabodies in the mammalian cytoplasm. Lee S, Kaku Y, Inoue S, Nagamune T, Kawahara M. Biotechnol J 11 565-573 (2016)
  17. Quantitative Analysis of the Microtubule Interaction of Rabies Virus P3 Protein: Roles in Immune Evasion and Pathogenesis. Brice A, Whelan DR, Ito N, Shimizu K, Wiltzer-Bach L, Lo CY, Blondel D, Jans DA, Bell TD, Moseley GW. Sci Rep 6 33493 (2016)
  18. Minimal Elements Required for the Formation of Respiratory Syncytial Virus Cytoplasmic Inclusion Bodies In Vivo and In Vitro. Galloux M, Risso-Ballester J, Richard CA, Fix J, Rameix-Welti MA, Eléouët JF. mBio 11 (2020)
  19. Oligomerization of Mumps Virus Phosphoprotein. Pickar A, Elson A, Yang Y, Xu P, Luo M, He B. J. Virol. 89 11002-11010 (2015)
  20. Structure of the C-terminal domain of lettuce necrotic yellows virus phosphoprotein. Martinez N, Ribeiro EA, Leyrat C, Tarbouriech N, Ruigrok RW, Jamin M. J. Virol. 87 9569-9578 (2013)
  21. Vesicular Stomatitis Virus Phosphoprotein Dimerization Domain Is Dispensable for Virus Growth. Gérard FCA, Jamin M, Blackledge M, Blondel D, Bourhis JM. J Virol 94 (2020)
  22. Measles Virus Forms Inclusion Bodies with Properties of Liquid Organelles. Zhou Y, Su JM, Samuel CE, Ma D. J. Virol. 93 (2019)
  23. Prokaryotic Expression, Purification, and Polyclonal Antibody Production of a Truncated Recombinant Rabies Virus L Protein. Zhang J, Jin Z, Sun T, Jiang Y, Han Q, Song Y, Chen Q, Xia X. Iran. J. Biotechnol. 13 18-24 (2015)
  24. Structural Description of the Nipah Virus Phosphoprotein and Its Interaction with STAT1. Jensen MR, Yabukarski F, Communie G, Condamine E, Mas C, Volchkova V, Tarbouriech N, Bourhis JM, Volchkov V, Blackledge M, Jamin M. Biophys J 118 2470-2488 (2020)
  25. Against the odds? De novo structure determination of a pilin with two cysteine residues by sulfur SAD. Gorgel M, Bøggild A, Ulstrup JJ, Weiss MS, Müller U, Nissen P, Boesen T. Acta Crystallogr. D Biol. Crystallogr. 71 1095-1101 (2015)
  26. Cryo-EM structure of the respiratory syncytial virus RNA polymerase. Cao D, Gao Y, Roesler C, Rice S, D'Cunha P, Zhuang L, Slack J, Domke M, Antonova A, Romanelli S, Keating S, Forero G, Juneja P, Liang B. Nat Commun 11 368 (2020)
  27. Structural and Functional Characterization of the Phosphoprotein Central Domain of Spring Viremia of Carp Virus. Wang ZX, Liu SB, Guan H, Lu LF, Tu JG, Ouyang S, Zhang YA. J Virol 94 (2020)