› 3l19

X-ray diffraction
2.14Å resolution

Crystal structure of calcium binding domain of CpCDPK3, cgd5_820

Released:
DOI: 10.2210/pdb3l19/pdb
PDB 3l19 coloured by chain and viewed from the front.
PDB 3l19 coloured by chain and viewed from the side.
PDB 3l19 coloured by chain and viewed from the top.
Source organism: Cryptosporidium parvum Iowa II
Entry authors: Qiu W, Hutchinson A, Wernimont A, Walker JR, Sullivan H, Lin Y-H, Mackenzie F, Kozieradzki I, Cossar D, Schapira M, Senisterra G, Vedadi M, Arrowsmith CH, Bountra C, Weigelt J, Edwards AM, Bochkarev A, Hui R, Amani M, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
homo dimer
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calcium/calmodulin dependent protein kinase with a kinase domain and 4 calmodulin like EF hands Chains: A, B
Molecule details ›
Chains: A, B
Length: 214 amino acids
Theoretical weight: 24.21 KDa
Source organism: Cryptosporidium parvum Iowa II
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5CS01 (Residues: 325-520; Coverage: 38%)
Gene name: cgd5_820
Sequence domains: EF-hand domain pair

Ligands and Environments

3 bound ligands:
Ligand CA 8 x CA
Ligand GOL 4 x GOL
Ligand 1PE 1 x 1PE
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-B
Spacegroup: C2
Unit cell:
a: 92.57Å b: 64.187Å c: 72.807Å
α: 90° β: 97.86° γ: 90°
R-values:
R R work R free
0.216 0.216 0.257
Expression system: Escherichia coli

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